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In vitro drug conversation reports have shown that mitoxantrone did not inhibit CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 and 3A4 throughout a broad concentration array. The effects of in vitro induction experiments are inconclusive, but advise that mitoxantrone may be a weak inducer of CYP450 2E1 activity. Pharmacokinetic scientific tests from the inte

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